After a brief experience in Inditex group (Zara), Jorge began his design studies in Madrid and then in the USA. At the age of 23 he won the first prize of the "IV Mostra de Novos Creadores de Moda" awarded by the Xunta de Galicia. From 1995 to 1998 he collaborated with the Design Department of the Galician firm Antonio Pernas. He later moved to Madrid to be part of the creative team of the firm Angel Schlesser.
He worked as coordinator of the design department of Fecón. Later he moved into the world of accessories and accessories with fun & Basics, and at the same time launched his own collection of female prêt-à-porter. In February 2002 Jorge Vázquez presented his first collection under his own name on the Pasarela Cibeles (now MBFWM).
His sixth fashion show (spring-summer 2005 collections for women and men) was awarded the L'OREAL Prize for Best Collection and Young Designer. At the same time Jorge Vázquez combined the presentation of his collections in Cibeles with a collaboration with the INDUYCO group, being the creative responsible for the event and party collections for the BRAND SÍNTESIS. During 2006 he collaborated with LOEWE to design the women's collection. In 2009 he launched his first collection of the 'JV Petit Couture' line for little girls.
In 2014 he joined El Corte Inglés, a leading Spanish textile company, as coordinator and supervisor of the group's women's firms. In 2016 Jorge Vázquez returns to the MBFWM after 10 years, presenting his collection JV by Jorge Vázquez Otoño-Winter 2016/17, which was awarded the L'Oreal price to the best collection.
Currently, he continues his project under the brand JV by Jorge Vázquez and his line of Haute Couture, and since January 2020 he is creative director of the heritage maison Pertegaz.